Leszek Lisowski

Company: Children's Medical Research Institute

Job title: Unit Head, Translational Vectorology Research Unit

Bio:

Associate Professor Lisowski is a global expert in development and manufacturing of novel bioengineered AAV vectors as well as in development and translation of AAV-based therapies for rare paediatric genetic conditions. In addition to his academic career, Dr Lisowski has established and is involved in a number of commercial companies, including clinical-grade manufacturing facility, and plays also active roles in a number of philanthropic organisations that aim to help children affected by genetic disorders.

Seminars:

Showcasing Less Liver-Tropic Development Efforts for IV-Administered Vectors 8:00 am

Outlining the latest rational design and natural variants methods for AAV vector engineering Highlighting a range of vector bioengineering efforts Covering liver, CNS, and ocular focused vector development, as well as T cells for CAR-T developmentRead more

day: Conference Day One

De-Risking the Human Translatability Piece of Next-Generation Vectors 8:35 am

Highlighting different approaches to produce robust, translatable data when transitioning through preclinical studies Better understanding disease mechanisms and anticipated clinical responses to guide vector selection and design Exploring more predictive preclinical models (e.g., human cells, organoids, assembloids) for both vector validation and development Outlining the role of vector bioengineering for fit-for-purpose human tissue types Reducing…Read more

day: PRE-CONFERENCE WORKSHOP DAY