Improved AAV Vector Design to Manage Systemic Toxicity & Immunogenicity

Time: 11:05 am
day: PRE-CONFERENCE WORKSHOP DAY

Details:

  • Determining which vector components trigger toxicities and immune responses
  • Capsid and payload optimization strategies to reduce toxicity and immunogenicity
  • Understanding the latest tissue targeting and de-targeting vector design approaches to evade the liver
  • Tissue tropism considerations for choosing a route of administration
  • Validating novel vectors to progress to the clinic

Speakers: