Human-Evolved AAV Vectors to Access Specific Neural Circuits
Time: 10:45 am
day: Conference Day Two
Details:
- Targeting specific components of the nervous system provides a gateway to safely treat numerous disorders that have a high unmet need
- Our novel technology platform, R-Scan, recreates human neural circuits and allows us to evolve novel AAV vectors specifically targeted to those cell types
- Our first use case has been in motor neurons, and our capsids efficiently target these neurons in vitro and in vivo without off target biodistribution
