8:00 am Workshop Check-In & Coffee Networking
8:30 am Workshop A
Gaining Control through Rational Design: What are the Best Approaches to Vector Design?
Synopsis
The design of capsids and payloads is vital to address factors impacting therapeutic safety as well as reducing costs and time of development. Previous methods for design were largely random with limitations in understanding its mechanism of action. With the field now leaving this methodology in the past, what are the rational design approaches that can be employed? How do these improve vector efficacy and safety?
Join to benefit from:
- Discovering various rational strategies for designing with receptors or ligands in mind to optimize capsid design
- Identifying how rational design for capsids and payloads can limit off-target effects and immunogenicity while improving efficacy and safety
- Understanding how moving towards rational design can reduce costs and decrease the time to reach the clinic
10:30 am Morning Break & Networking
11:00 am Workshop B
Utilizing AI to Accelerate Rational Development: How can AI Optimize Gene Therapy Vectors?
Synopsis
Developing effective vector therapies in a time- and cost-efficient manner is key to propelling vector therapy’s potential. AI and machine learning are already streamlining therapeutic development in many fields. Capitalizing on the progression of AI is a great avenue to enhance the efficiency of vector therapy design and development. Given AI’s emerging role in this field, it is crucial to highlight: What are the current successes utilizing machine learning? How can AI be integrated into all stages of vector development?
Join to benefit from:
- Discussing what AI strategies are being used to enhance different stages of capsid and payload development
- Understanding how these strategies are improving vector efficacy and promoting cost and time efficiency
- Exploring future goals for AI in vector development to further enhance vector development
1:00 pm Lunch Break & Networking
2:00 pm Workshop C
When Two Become One: How Does Capsid & Payload Design Collaboration Improve Translational Success?
Synopsis
For a vector to be effective, both the capsid and payload must be functional. However, the expertise required to engineer each part of the vector differs significantly, often leading to divisions in the field. This drives inefficient vector development and can increase costs. It is therefore key to investigate the following questions: How can collaborations reduce development time and cut costs? How does co-operation across biopharma improve vector efficacy?
Join to benefit from:
- Examining the interplay between payload and capsid to design better vectors
- Evaluating successful biopharma collaborations across payload and capsid development
- Reflecting on how collaboration during development could enhance vector efficacy, safety, and cut costs