Improved AAV Vector Design to Manage Systemic Toxicity & Immunogenicity
Time: 11:05 am
day: PRE-CONFERENCE WORKSHOP DAY
Details:
- Determining which vector components trigger liver toxicity and immune responses
- Capsid and payload optimization strategies to reduce toxicity and immunogenicity
- Understanding the latest tissue targeting and de-targeting vector design approaches to evade the liver
- Tissue tropism considerations for choosing a route of administration
- Levelling up characterisation and tissue tropism validation of novel vectors
Speakers:
