Daniel Cohen

Company: Spark Therapeutics, Inc.

Job title: Head of Vector Optimization

Bio:

As Head of Vector Optimization, Dr. Daniel Cohen leads a team at Spark Therapeutics that focuses on enhancing the safety and efficacy of gene therapies by the intelligent design of DNA payloads. This includes building technologies to improve the sequences of transgenes, promoters, and other non-coding elements, as well as generation of gene switches enabling the delivery of transgenes where precise control over the timing and amount of gene expression is possible.

Seminars:

Optimizing Overall Vector Efficacy with Promoter Selection & Engineering 2:30 pm

Outlining how promoter engineering enhances transgene expression Understanding how promoter strength and vector dose affect the predictability of gene therapy Exploring effects of promoters on ON-target versus OFF-target gene expressionRead more

day: Conference Day One