Solving For AAV Tissue Tropism With The AAVidTM Capsid Discovery Platform

Time: 9:30 am
day: Day Two AM


• The AAVid platform leverages massive diversity libraries to map the AAV landscape directly in NHPs in an unprecedented way

• Machine learning on biological selection data across 48 tissues in 4 NHPs enables identification of sequence features in AAV variants that drive unique tissue tropism profiles

• Tissue tropism profiles (e.g., CNS, heart, CNS + heart, etc.) validation in NHP secondary screening and single-candidate experiments